Jun 6, 2025
11:00am - 12:00pm
PDT

DisrupTV is a weekly podcast with hosts R "Ray" Wang and Vala Afshar. The show airs live at 11:00 a.m. PT/ 2:00 p.m. ET every Friday. The audience can expect A-list guests, the latest enterprise news, hot startups, insight from influencers, and much more. Tweet questions to #DisrupTV or @DisrupTVShow. We broadcast live on StreamYard. 

Show Link: https://www.youtube.com/user/ConstellationR

Featured Guests:

Karen Silverman
CEO and Founder
The Cantellus Group

Karen is a leading global expert in practical governance strategies for AI and other frontier technologies. As the CEO and Founder of The Cantellus Group, she advises Fortune 50 companies, startups, consortia, and the public sector on how to manage cutting-edge technologies in a rapidly changing policy environment. Her expertise is informed by more than 20 years of practice and management leadership at Latham & Watkins, LLP where she advised global businesses in complex antitrust matters, M&A, governance, ESG, and crisis management.

Karen serves on the ABA Task Force on the Law and Artificial Intelligence, was a World Economic Forum Global Innovator and a member of their Experts Network and an SME to the Business Roundtable. She sits on the Fast Company Impact Council and serves on the board of AIEDU and Not For Sale and sits on the Advisory Board of Legal Momentum. She is a frequent speaker and author on technology and corporate governance issues.

Denise Holt
Founder and CEO of AIX Global Media

Denise Holt is a futurist educator, strategic advisor, and the visionary founder of AIX Global Media and Learning Lab Central by E-mmersion Publishing — the world’s leading education platform for Active Inference AI and the Spatial Web Protocol.

With a career spanning three decades at the intersection of technology, media, and innovation, Denise has become the foremost voice educating the world on the next evolution of intelligence — one that’s explainable, adaptive, decentralized, and deeply aligned with the physical world.

She is the architect of the first and only Executive Certification Program in Active Inference AI and Spatial Web Technologies, delivering in-depth, enterprise-ready education to business leaders, developers, and global innovators. Her structured 7-course program breaks down complex scientific frameworks like Renormalizing Generative Models (RGMs) and the Free Energy Principle, translating them into strategic insight and operational advantage for the next generation of intelligent systems.

Denise is also the creator and host of Learning Lab LIVE, a twice-monthly broadcast and discussion series that has featured thought leaders including VERSES AI’s Dan Mapes and researchers across the fields of neuroscience, AI safety, and spatial computing.

A relentless systems thinker with a background in both startup innovation and enterprise transformation, Denise isn’t following the trend — she’s defining the trajectory. Her mission is to ensure that every organization has access to the knowledge and tools required to thrive in a world of context-aware, real-time Intelligent Agents and distributed AI systems.

"Active Inference AI, with its distributed intelligence, is a transformative force. Business leaders and technologists who remain unaware of decentralized AI and the convergence of emerging tech in this next era of computing, risk falling behind. The sooner you grasp the impact these technologies will have on your industry, the better positioned you’ll be to lead and stay ahead."

“We are not just teaching the future of AI — we’re teaching the intelligence layer of the next evolution of our internet.”
— Denise Holt

 

Dr. David Bray
Distinguished Chair of the Accelerator, Stimson Center
& Principal/CEO, LDA Ventures Inc.

Dr. David A. Bray is a Distinguished Fellow and Chair of the Accelerator with the Alfred Lee Loomis Innovation Council at the non-partisan Henry L. Stimson Center. He is also a non-resident Distinguished Fellow with the Business Executives for National Security, and a CEO and transformation leader for different “under the radar” tech and data ventures seeking to get started in novel situations. He is Principal at LeadDoAdapt Ventures and has served in a variety of leadership roles in turbulent environments, including bioterrorism preparedness and response from 2000-2005. Dr. Bray previously was the Executive Director for a bipartisan National Commission on R&D, provided non-partisan leadership as a federal agency Senior Executive, worked with the U.S. Navy and Marines on improving organizational adaptability, and aided U.S. Special Operation Command’s J5 Directorate on the challenges of countering disinformation online. He has received both the Joint Civilian Service Commendation Award and the National Intelligence Exceptional Achievement Medal. David accepted a leadership role in December 2019 to direct the successful bipartisan Commission on the Geopolitical Impacts of New Technologies and Data that included Senator Mark Warner, Senator Rob Portman, Rep. Suzan DelBene, and Rep. Michael McCaul. From 2017 to the start of 2020, David also served as Executive Director for the People-Centered Internet coalition Chaired by Internet co-originator Vint Cerf and was named a Senior Fellow with the Institute for Human-Machine Cognition starting in 2018. Business Insider named him one of the top “24 Americans Who Are Changing the World” under 40 and he was named a Young Global Leader by the World Economic Forum. For twelve different startups, he has served as President, CEO, Chief Strategy Officer, and Strategic Advisor roles.

David’s passions include complicated, near-impossible missions involving humans and technology in challenging circumstances. Through the efforts of a team of “positive change agents”, he led the transformation of the Federal Communication Commission’s legacy IT with more than 207 different systems to award-winning tech. This included rolling out new cloud-based IT that achieved results in 1/2 the time at 1/6 the cost. He was the recipient of the Armed Forces Communications and Electronic Association’s Outstanding Achievement Award for Civilian Government. He also received the global CIO 100 Award twice, which usually is awarded to private sector Fortune 500 companies, both in 2015 and 2017, for his transformational leadership in change-adverse settings. From 2017-2021, he both worked with multiple services associated with the U.S. Department of Defense on improving organizational adaptability and countering disinformation online – including personally surviving a disinformation attack that occurred in 2018. In 2019, he was invited to give the AI World Society Distinguished Lecture to the United Nations on UN Charter Day.

As Principal at LeadDoAdapt Ventures, Dr. Bray’s passions include providing Board-level and CEO-level leadership to different “under the radar” tech and data ventures seeking to get started in novel situations to include activities that shape the Future of Data, Bio, and Space. He provides strategic direction, advice, and leadership to organizations confronting turbulent environments on multiple topics ranging from quantum computing to commercial space endeavors; synthetic biology to data cooperatives paired with AI. He accepted a role of Co-Chair for 2016-2017 with an IEEE Committee focused on Artificial Intelligence, automated systems, and innovative policies globally and has been serving as a Visiting Executive In-Residence at Harvard University since 2015 and as a Faculty Member giving talks on Impact and Disruption at Singularity University since 2017. In 2021 and 2022, he was named a Distinguished Fellow with the Atlantic Council. In 2023, he was named a distinguished Academy Fellow with the National Academy of Public Administration focused on the role of transformative technologies, like AI, on public service. In 2022, the Business Executives for National Security welcomed him as a Distinguished Fellow focused on the intersection of transformative technologies, global collaborations, and over-the-horizon challenges for the future ahead. David has been an invited keynote speaker to CEOs, world leaders, and crowds of more than 3,000 participants at events in India, Vietnam, Australia, Taiwan, Dubai, South Africa, Brazil, Colombia, Mexico, Canada, Belgium, Sweden, Singapore, Saudi Arabia, Switzerland, and the United Kingdom.

 

Lori Rosenkopf
Author of Unstoppable Entrepreneurs: 7 Paths for Unleashing Successful Startups and Creating Value through Innovation

Lori Rosenkopf is the Simon and Midge Palley Professor at the Wharton School of the University of Pennsylvania. As Vice Dean for Entrepreneurship, she serves as Wharton’s faculty director for Venture Lab, Penn’s home for student entrepreneurs, and also their San Francisco campus. In a prior role as Vice Dean of Wharton’s Undergraduate Division, she introduced a new curriculum and developed experiential classwork in the tech sector. For over thirty years, Rosenkopf has taught entrepreneurship and management of technology to more than 20,000 high schoolers, undergraduates, MBAs, and executives, connecting these learners to many of the most entrepreneurial alumni at Wharton and Penn through treks, panels, and classes.

Rosenkopf was named a Best Undergraduate Professor by Poets and Quants, and has received multiple awards for her teaching, including Wharton’s prestigious David Hauck Award for Distinguished Teaching. Rosenkopf has published more than thirty articles on technological communities and social networks in top management journals, and she is a Fellow of the Academy of Management.

Rosenkopf received her PhD in Management of Organizations from Columbia University, her MS in Operations Research from Stanford University, and her BS in Operations Research and Industrial Engineering from Cornell University. She worked as a systems engineer at AT&T Bell Laboratories and Eastman Kodak between her degrees. Rosenkopf lives in Philadelphia with her partner, Allan, and their dog, Winston.